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day three human embryo on a tip of a dressmaker's pin
Preparation of small samples that are invisible to the naked eye presents a challenge in electron microscopy.

Human and other mammalian eggs and early embryos have been successfully prepared in our laboratory.

We employ several innovative techniques to observe these
small objects, which include:

- placing embryos on the tip of a standard dressmaker's pin, allowing for a maximum of their surface to be examined.

- cracking the trophoblast to expose the blastocyst's cavity
and visualize the inner cell mass.

- placing a blastocyst on a piece of endometrium to develop an ex-vivo model to study the implantation process in the human.

[publication 29 and 34]

  assessment   assessment  
  inner cell mass of a human day five blastocyst   day six human blastocyst attached to endometrial tissue

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